Examinando por Materia "MICROFABRICATION"

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    Engineering materials surfaces by microfabrication techniques, to regulate in vitro cell functions: review
    (2014-05-07) Gallego, D. (Diego); Hansford, D. (Derek)
    Ha quedado claro que las propiedades superficiales de los materiales utilizados como sustratos para cultivo celular pueden influir en el comportamiento de las células afectando diferentes factores tales como la orientación celular, adhesión, crecimiento, diferenciación y apoptosis. En los últimos años, varias técnicas de microfabricación y nanofabricación han emergido como herramientas importantes usadas para modificar las propiedades superficiales de esos materiales en la escala micrométrica y nanométrica, ya sea topográfica o químicamente. Este artículo revisa las técnicas de microfabricación mas usadas para introducir modificaciones en las superficies de los materiales y sus implicaciones en el comportamiento celular. Esta revisión termina mostrando las posibles aplicaciones médicas derivadas como una fuente de futuros desarrollos en este campo.
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    PublicaciónAcceso abierto
    Fabricación de microagujas en fotorresina SU-8 mediante fotolitografía para aplicaciones biomédicas
    (2014-04-20) Lopera-Aristizábal, M. (Mónica); Lopera-Aristizábal, S. (Sergio); Vélez-Restrepo, J. M. (Juan Manuel )
    Hormonal illnesses like diabetes demand the frequent use of fluid sampling and drug delivery procedures, which produces traumas on skin tissues, as a result of conventional needles penetration. This fact motivates the development of alternative technologies that decrease tissue damage and contribute to improve the quality of life of the patients. This topic constitutes an active field of research in many companies and universities around the world. This paper presents preliminary results of the fabrication of microneedle arrays, using the technique of SU-8 thick film photolithography, previously standardized by the Group of Materials Science and Technology of the National University of Colombia in Medellín. Micrographs of the obtained hollowed and solid needles of different sizes are presented and goals and limitations of the proposed methodology are discussed.
  • Miniatura
    PublicaciónAcceso abierto
    Interfaces neuronales y sistemas máquina-cerebro: fundamentos y aplicaciones. Revisión
    (2014-04-19) García-Quiroz, F. (Felipe); Villa-Moreno, A. (Adriana); Castaño-Jaramillo, P. (Paula)
    Abstract—During the past ten years the Neural Interfaces and brain-computer communication systems area has become an important field for research, in part due to the increasing statistics of motor and sensorial disabilities. The development of these systems and interfaces requires the coordinated work of different areas such as physiology, materials science, instrumentation and signal processing, computational intelligence, mechanics, electronics, robotics, and informatics, among others. They allowed the right integration between the nervous system physiology, the construction of biocompatible electrodes, the acquiring of proper signals for processing, the classification and identification of coded patterns and the design of the actuators elements to finally achieve the goal of the interface. In this review the three basic stages of neural interfaces are shown. This includes: signal acquiring, signal processing and the wide variety of applications with the effectors systems.